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  • Active Pharmaceutical Ingredient (API) refers to the biologically active component of a pharmaceutical drug. It is the key ingredient responsible for the therapeutic effect of the medication. APIs are synthesized through various chemical and biotechnological processes and are used in the production of various dosage forms, including tablets, capsules, injections, and topical formulations. These ingredients are crucial for the development and manufacture of pharmaceutical drugs. APIs undergo rigorous research and development processes to ensure their safety, efficacy, and quality. Initially, scientists identify potential compounds with therapeutic properties through drug discovery and screening processes. Once a promising compound is identified, it undergoes extensive testing in preclinical studies to assess its pharmacological activity, toxicity, and potential side effects.

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    Overview:
    Common Name: N,N,N,N-Tetramethylguanidine
    Other Chemical Names:
    N,N-Tetramethylguanidine;1,1,3,3-TetramethylGuanidine(TMG);1,1,3,3-Tetramethylgyanidine, 1,1,3,3-TetrChemicalbookamethylguanidine, ;N,N,N,N-Tetramethy1Guanidine; 1,1,3,3-Tetramethylguanidin; TMG; 1,1,3tetramethylguanidine
    MF:C5H13N3
    MW:115.18
    CAS:80-70-6

    Typical Properties

    Appearance Form: liquid
    Colour: light yellow
    PH 12.7 at 10 g/l at 25 °C
    Melting point/freezing point Melting point/range: -80 °C at 1,013 hPa
    Initial boiling point
    and boiling range 162 - 163 °C - lit.
    162 °C at 1,013 hPa
    Flash point 50 °C - closed cup
    Density 0.916g/cm3 at 20℃
    Vapour pressure 2.9 hPa at 20 °C


    Description
    In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non-nucleophilic base. 1,1,3,3-tetramethylguanidine is an efficient and selective catalyst for alcohol benzoylation.
    Physical and chemical properties tetramethylguanidine is a colorless oily liquid, boiling point 160-162℃, density 0.918, refractive index 1.4692, is a strong organic base, soluble in toluene, cyclohexanone, ethanol, etc., also Chemicalbook soluble in water, easily hydrolyzed to tetramethyl urea in alkaline aqueous solution, corrosive, generally packed in galvanized iron drums.
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    TMG N,N,N,N-Tetramethylguanidine CAS No.: 80-70-6 N,N,N,N-Tetramethylguanidine CAS No.: 80-70-6 Overview: Common Name: N,N,N,N-Tetramethylguanidine Other Chemical Names: N,N-Tetramethylguanidine;1,1,3,3-TetramethylGuanidine(TMG);1,1,3,3-Tetramethylgyanidine, 1,1,3,3-TetrChemicalbookamethylguanidine, ;N,N,N,N-Tetramethy1Guanidine; 1,1,3,3-Tetramethylguanidin; TMG; 1,1,3tetramethylguanidine MF:C5H13N3 MW:115.18 CAS:80-70-6 Typical Properties Appearance Form: liquid Colour: light yellow PH 12.7 at 10 g/l at 25 °C Melting point/freezing point Melting point/range: -80 °C at 1,013 hPa Initial boiling point and boiling range 162 - 163 °C - lit. 162 °C at 1,013 hPa Flash point 50 °C - closed cup Density 0.916g/cm3 at 20℃ Vapour pressure 2.9 hPa at 20 °C Description In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non-nucleophilic base. 1,1,3,3-tetramethylguanidine is an efficient and selective catalyst for alcohol benzoylation. Physical and chemical properties tetramethylguanidine is a colorless oily liquid, boiling point 160-162℃, density 0.918, refractive index 1.4692, is a strong organic base, soluble in toluene, cyclohexanone, ethanol, etc., also Chemicalbook soluble in water, easily hydrolyzed to tetramethyl urea in alkaline aqueous solution, corrosive, generally packed in galvanized iron drums. Applications NT CAT TMG can also be used as a catalyst for polyurethane foam and for even dyeing of nylon, wool and other proteins to improve the durability of wool, etc. It is mainly used in the synthesis of cefradine and other drugs. Storage Information NEWTOP Chemical recommends that our catalysts be stored in a dry and cool area under appropriate ventilation conditions. Each container should be closed tightly to avoid contamination with moisture or other negative influences that could change the products performance in the end use. The optimum storage temperature is between 10 °C and 30° C. Lower and higher storage temperatures are not preferable and should be avoided. Shelf Life: 24 Months Standard Packaging: 180KG Steel Drum 900KG IBC Drum Sample contact:info@newtopchem.com More:https://www.newtopchem.com/archives/42570
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  • N-methyl-Methylcyclohexylamine CAS 100-60-7
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    N-methyl-Methylcyclohexylamine CAS 100-60-7

    Descriptions:
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    Molecular Formula:C7H15N ( Isomeride)
    Molecular Weight:113.204
    EINECS:202-869-3
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    Physicochemical properties
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    Appearance:transparent and colorless liquid
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    Physical Property:transparent and colorless liquid, Miscible with various organic solvents, slightly soluble in water。Melting point:−9-−7 °C(lit.) Boiling point:149 °C(lit.) Density:0.868 g/mL at 25 °C(lit.) Refractive index:n20/D 1.456(lit.) Flash point:85 °F Water solubility:5.4 g/100 mL (20 ºC) transparent and colorless liquid. Miscible with various organic solvents, slightly soluble in water。 transparent and colorless liquid。 Boiling point 147~151℃ Relative density 0.868 Refractive index 1.4456 Flash point 29℃ Solubility Miscible with various organic solvents, slightly soluble in water
    Solubility:Slightly soluble in water, soluble in benzene, alcohol, etc

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    N-methyl-Methylcyclohexylamine CAS 100-60-7 Descriptions: Synonyms: Cyclohexylmethylaminecyclohexyl-methyl-aminemethylcyclohexylamine,[corrosivelabel]Cyclohexylamine,N-methyl-1-MethylcyclohexylamineCyclohexanamine,N-methyl-MethylcyclohexylamineN-Cyclohexylmethylamine CAS No.:100-60-7 Molecular Formula:C7H15N ( Isomeride) Molecular Weight:113.204 EINECS:202-869-3 Category:Pharmaceutical Intermediates Physicochemical properties Density:0.868 Melting point:-8℃ Boiling point:149℃ Refractive index:1.4545-1.4565 Flash point:29℃ Vapor pressure:4.62mmHg at 25°C PSA:12.03000 logP:1.92940 Appearance:transparent and colorless liquid Color: colorless liquid Physical Property:transparent and colorless liquid, Miscible with various organic solvents, slightly soluble in water。Melting point:−9-−7 °C(lit.) Boiling point:149 °C(lit.) Density:0.868 g/mL at 25 °C(lit.) Refractive index:n20/D 1.456(lit.) Flash point:85 °F Water solubility:5.4 g/100 mL (20 ºC) transparent and colorless liquid. Miscible with various organic solvents, slightly soluble in water。 transparent and colorless liquid。 Boiling point 147~151℃ Relative density 0.868 Refractive index 1.4456 Flash point 29℃ Solubility Miscible with various organic solvents, slightly soluble in water Solubility:Slightly soluble in water, soluble in benzene, alcohol, etc Application: Used as intermediates in medicine and dyes Pharmaceutical and dye intermediates. Used as an intermediate in the drug bromohexamine hydrochloride Production Method: With cyclohexylamine as raw material prepared. 2. By the reaction of cyclohexanone and methylamine. Soak aluminum sheet in methanol, add high mercury chloride, continue to soak 2h, temperature rise does not exceed 55℃, remove the soaking liquid. Add ethanol to the activated aluminum sheet, drop the mixture of methylamine and cyclohexanone under agitation, heat reflux, and place overnight. Adding 10% sodium hydroxide solution alkalization, extracting with benzene twice, after washing by distillation, benzene recovery that distillation of n-methyl cyclohexylamine. The yield is about 80%. ; Storage and transport information:: It should be sealed and stored in a dry and cool ventilated warehouse Packaging: 200KG/ drum storage: It is recommended to store in dry and cool areas and properly ventilated. After the original packaging, please fasten the packaging cover as soon as possible to prevent moisture and other substances from mixing and affecting the product performance. Do not inhale dust and avoid skin and mucous membrane contact. Smoking, eating and drinking are prohibited in the workplace. After work, shower and change. Store contaminated clothes separately and reuse them after washing. Maintain good hygiene. Contact Us SHANGHAI OHANS CO., LTD. Factory Address :Jining High-tech Development Zone, Shandong, China Call Center :021-5161-9971 Headquarters :Room a2110, building 55, No. 709, Lingshi Road, Zhabei District, Shanghai Email Us :honda@ohans.com candy@ohans.com More:https://www.ohans.com/n-methyl-methylcyclohexylamine-cas-100-60-7-pdf/
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